BioMind

From Biocompany.net

Biomind — leading the way in clinical and biological knowledge extraction from high-volume genetics data

ArrayGenius, Biomind's flagship product, is an enterprise software system for microarray data analysis. ArrayGenius combines advanced machine learning algorithms with massive volumes of background information, including biological ontologies, to deliver straightforward but powerful analysis.

Applications

• Biomarker Discovery, including cases where biomarkers involve complex multiple gene interactions

• Biological Processes Interpretation, including dynamics and pathways underlying diseases and other phenotypic characteristics

• Personalized Medicine, including identification of individuals likely to suffer toxic reactions to particular drugs

• Fundamental Research, including gene function and metabolic pathway research

Product Highlights

• Classification Accuracy which is industry-best (general clinical, and clinical toxicological, and general/non-clinical)

• Powerful Reporting which condenses and summarizes results from complex analysis, including clustering and classification

• Most Important Features extraction from experimental data, including genes, gene products and biological processes

• Classification Rule Learning for predicting biological or clinical subject classification based on genetic and clinical profile data

• Utilization Clusters of genes or gene products which tend to be found together in the context of biological phenomenon under study

The most important features reporting function, which highlights individual features common among hundreds or thousands of supervised classification models (classification model ensembles), is unique to ArrayGenius, and provides deeper insight when compared with rudimentary analytical methods such as tabulation or clustering of most highly expressed genes.

ArrayGenius OnDemand is available for live use by subscription—sign up online for a free trial! ArrayGenius is also available as an enterprise application installed on qualifying Linux platforms. Please contact sales@biomind.com for pricing and further options.

GeneGenius applies an ArrayGenius-type methodology to SNP analysis, providing immeasurable value in the case of complex diseases where no
individual SNP provides much information, yet combinations of SNP's do effectively characterize conditions of interest (such as diseases).

As an indication of the value of the ArrayGenius and GeneGenius methods, during 2003-2005 the ArrayGenius was used in collaboration
with the Centers for Disease Control and Prevention to make a series of discoveries regarding Chronic Fatigue Syndrome, reported in a
series of publications in Pharmacogenomics.  And, Biomind staff are currently in the process of integrating ArrayGenius methods into the
ImmPort portal launched by NIH-NIAD.

OntoloGenius, Biomind's most recent product, is a software toolkit for inferring gene membership in gene ontology categories. To display the usefulness of this approach, Biomind applied OntoloGenius to our integrated database of public microarray datasets, making provisional GO assignments for many human and yeast genes, and published the results at go.biomind.com as an Enhanced Gene Ontology.

Analytic Services are available from Biomind. Our customers include the Centers for Disease Control and Prevention, the University of Virginia, the University of Texas, and Northrop-Grumman.  Please contact sales@biomind.com to learn how Biomind can enhance your data analysis abilities.